Wednesday, August 29, 2018

Designing a 3-Lead Cost Effective ECG Recording Glove for Home Monitoring  

Madiha Yunus, Amna Talib and Arsalan Khan, Sir Syed University of Engineering and Technology, Pakistan

ABSTRACT 

The EKG Glove is a wearable glove-based device on which all the necessary electrodes are pre-positioned hence the patient simply inserts his right hand into the glove and properly position the glove his chest to record a standard ECG. It is the first, lead wire free, simultaneous, and fully diagnostic ECG recording system in Pakistan with easy, natural and almost automatic placement of the electrodes, hence eliminating the difficulty of lead wire entanglement and electrode misplacement. 

KEYWORDS

 Electrocardiogram, Electrical Activity, Glove, Patient Ease, Medical Imaging


Wednesday, August 22, 2018

Optimizing the Medium Conditions For Production of Tetracycline By Solid State Fermentation of Streptomyces Aureofaciens NCIM 2417 Using Statistical Experimental Methods 

Basavaraj M. Vastrad1 and Shivayageeswar E. Neelagund2, 1S. E. T`s College of Pharmacy, India and 2Jnana Sahayadri Kuvempu University, India

Abstract 

Tetracycline belongs to one of the extracellular produced polyketide antibiotics having hydrophilic properties. Statistical based optimization, Plackett–Burman design (PBD) and response surface methodology (RSM) were occupied to screen and optimize the medium conditions for the production of tetracycline from Streptomyces aureofaciens NCIM 2417, using solid state fermentation. pineapple peel waste was used as both the curious solid support and carbon and nitrogen sources and inorganic salts for the growth of Streptomyces aureofaciens NCIM 2417. Based on the positive influence of the half normal plot obtained from PBD on tetracycline production, three medium conditions – peanut meal, incubation period and soluble starch were screened. Central composite design (CCD) was occupied using these three medium conditions at five levels, for advance optimization, and the second order polynomial equation was derived, based on the experimental data. Response surface methodology showed that the conditions of peanut meal (0.4%), incubation period (day 2) and soluble starch (2%) were the optimal levels for maximal tetracycline production (17.98 mg/g substrate) which were validated through experiments. 

Keywords

Streptomyces aureofaciens NCIM 2417, solid state fermentation, pineapple peel, Placket Burman design, central composite design


Tuesday, August 21, 2018

Qsar Studies on Gallic Acid Derivatives and Molecular Docking Studies of Bace1 Enzyme – A Potent Target of Alzheimer Disease  

KrishnaKant Gupta, Pondicherry University, India

Abstract 

It is reported that Alzheimer disease is linked with hypertension, diabetes type 2 and high cholesterolemia. The underlying genetic cause relating these diseases are not well studied clinically. But it has been widely accepted that beta secretase (BACE1) is the main culprit of causing Alzheimer disease. This enzyme comes under peptidase A1 family. In the present work, ligand based and structure based drug designing have been reported. QSAR studies were done using 21 gallic acid derivatives dataset to develop good predictive model in order to predict biological activity and certain descriptors was reported to further enhance the analgesic activity of gallic acid derivatives. Molecular docking studies were performed in order to find structure based drug design. Two natural gallic acid derivative have been repoted as a potent inhibitor to beta secretase enzyme.

 Keywords:

 Alzheimer Disease, beta secretase, QSAR, Molecular docking, Ligands, inhibitor. 


Monday, August 20, 2018

Why Just Teach Art: The Development of the Hippocampus  

Judson Wright, Pump Orgin, USA

ABSTRACT 

That we intuitively feel a need to teach children what we consider the rudiments of education, approximately as soon as they are socially adept enough to attend school is not unjustified (eg. the “core curriculum standards” adopted by US public schools). However, there is a deeper technical issue to be considered, one that proves remarkably simple. Though the role of the hippocampus, within the larger function of the brain, is hardly well understood, there is ample evidence of its role in a particular aspect of memory, namely metacognition, or “knowing about knowing.” More neurologically informed consideration for the distinct memory systems that contribute to cognition revels that these rudiments may be entirely artificial and based on “adult-centric” conceptual frames. Moreover, given that the hippocampus is only fully formed by early adulthood, this would indicate that our educational itinerary may easily be fundamentally flawed, and at least warrants radical reconsideration. 

KEYWORDS

art education, concept development, hippocampus, memory systems 


Sunday, August 19, 2018

Antioxidant and Antimicrobial Activities Of Algerian Populus Nigra L. Buds Extracts  

Djamila Merghache, Zahia Boucherit-Otmani, Imad El Haci, Salima Merghache, Ilyas Chikhi and Kebir Boucherit,  University of Tlemcen, Algeria

ABSTRACT

This study is part of a goal to investigate chemical composition, antibacterial, antifungal and antioxidant activities of the flower buds extracts from the Algerian Polulus nigra L., which were collected from Djarifet - mansourah at Tlemcen city in the West Northern of Algeria. In organic extracts, tanins, flavonoïds, coumarins, alkaloids and terpenoïds were the principals secondary metabolites identified from the flower buds of black poplar. Antibacterial and antifungal activities of extracts were tested using agar-well diffusion method and micro-well determination of MIC assay against eleven bacteria and two Candida species. It was found that extracts of black poplar buds exhibit antibacterial and anticandidal activities with agar disk diffusion (7 to 43mm) and MIC methods (MIC= 90.33 µg/ml against several strains of bacteria and MIC=45.16 µg/ml against Candida albicans). The antioxidant effect of hydroalcoholic extract was evaluated using DPPH and FRAP assays. It was showed good and similar activity than ascorbic acid and BHA by DPPH method: IC50= 220µg/mL for hydroethanol extract. 

KEYWORDS: 

Populus nigra L. extracts, Antibacterial and antifungal activities, DPPH antioxidant power, Ferric reducing antioxidant power assay (FRAP). 


Friday, August 17, 2018



Low Power Class AB SI Power Amplifier for Wireless Medical Sensor Network  

Wei Cai1, Liang Huang2 and WuJie Wen3, 1University of California, USA, 2ZheJiang Gongshang University, China and 3Florida International University, USA



ABSTRACT 

The objective of this research was to design a 2.4 GHz class AB Power Amplifier (PA), with 0.18um Semiconductor Manufacturing International Corporation (SMIC) CMOS technology by using Cadence software, for health care applications. The ultimate goal for such application is to minimize the trade-offs between performance and cost, and between performance and low power consumption design. This paper introduces the design of a 2.4GHz class AB power amplifier which consists of two stage amplifiers. This power amplifier can transmit 10dBm output power to a 50Ω load. The power added efficiency is 7.5% at 1dB compression point and the power gain is 10dB, the total power consumption is 0.135W. The performance of the power amplifier meets the specification requirements of the desired. 

KEYWORDS 

Two stage, Class AB, Power amplifier, Healthcare